Officials believe someone threw the concrete chunk onto the road from a bridge, killing motorist Joe Shelton Jr, 54, as he drove to work on Tuesday.
The case is ongoing and investigators say they do not yet have a description of the person or group responsible.
Several motorists have died as a result of similar incidents in recent years.
When the concrete block – which officials believe came from a roadway kerb – landed on Mr Shelton’s car, it went through the windshield and caused the Nissan to swerve and hit a pickup truck and guardrail.
Last year, five Michigan teenagers were charged with second-degree murderfor flinging a 6lb (2.7kg) stone onto a car from a highway overpass, killing a 32-year-old man.